4-Bromo-2,6-difluorophenylboronic acid
Molecular Structure
Pricing & Availability
Specifications
| Catalog No. | RY110894 |
| CAS No. | 352535-81-0 |
| Molecular Formula | - |
| Molecular Weight | - |
| Purity | 95% |
| SMILES | OB(C1=C(F)C=C(Br)C=C1F)O |
| MDL Number | MFCD03095369 |
| Category | boronic |
| Availability | In Stock |
Synonyms & Alternative Names
Product Description
4-Bromo-2,6-difluorophenylboronic acid (CAS 352535-81-0) is a high-quality chemical intermediate offered by Raynchem for pharmaceutical, agrochemical, and material science research. The SMILES notation for 4-Bromo-2,6-difluorophenylboronic acid is OB(C1=C(F)C=C(Br)C=C1F)O, representing its complete molecular connectivity for computational chemistry and cheminformatics applications. Our 4-Bromo-2,6-difluorophenylboronic acid is available with a guaranteed purity of 95%, ensuring consistent and reliable results for your R&D and production needs. Each batch is accompanied by a Certificate of Analysis (COA) verifying identity, purity, and quality. Raynchem provides worldwide fast shipping, competitive pricing, and comprehensive technical support. COA and SDS documents are available upon request. Contact us today for bulk quantities and custom synthesis inquiries.
Applications
- ●Suzuki-Miyaura Cross-Coupling: 4-Bromo-2,6-difluorophenylboronic acid (CAS 352535-81-0) is an essential reagent for Suzuki-Miyaura coupling reactions, enabling the formation of carbon-carbon bonds in the synthesis of biaryl compounds, pharmaceuticals, and natural products.
- ●Pharmaceutical Synthesis: Boronic acid derivatives like 4-Bromo-2,6-difluorophenylboronic acid are key intermediates in the production of kinase inhibitors, protease inhibitors, and other therapeutic agents.
- ●Fine Chemical Manufacturing: 4-Bromo-2,6-difluorophenylboronic acid is suitable for scale-up from milligram to kilogram quantities, supporting both early-stage discovery and late-stage production needs.
Safety & Handling
Hazard Information
- !4-Bromo-2,6-difluorophenylboronic acid may cause mild irritation to skin, eyes, and respiratory tract.
- !Handle with standard laboratory precautions.
- !Contains bromine — may release hazardous decomposition products at high temperatures.
Precautionary Measures
- ✓Wear appropriate personal protective equipment (PPE): chemical-resistant gloves, safety goggles, and laboratory coat.
- ✓Work in a well-ventilated fume hood when handling 4-Bromo-2,6-difluorophenylboronic acid.
- ✓Avoid direct contact with skin, eyes, and clothing. Do not breathe dust, vapors, or aerosols.
- ✓Wash hands thoroughly after handling. Remove contaminated clothing before reuse.
This information is provided as a general guide. Always consult the Safety Data Sheet (SDS) for complete safety information before handling.
Storage & Stability
- ●4-Bromo-2,6-difluorophenylboronic acid should be stored in a cool, dry place away from direct sunlight and moisture.
- ●Keep the container tightly sealed when not in use to prevent degradation and contamination.
- ●Store separately from incompatible materials such as strong oxidizing agents, acids, and bases.
- ●Under proper storage conditions, the shelf life of this product is typically 24 months from the date of manufacture.